Cross-reactivity between Anisakis simplex sensitization and visceral larva migrans by Toxocara canis.
نویسندگان
چکیده
The aim of this work was to study cross-reactivity in the diagnosis of two related ascaridosis. Nineteen patients diagnosed with recidivous acute urticaria (RAU) caused by Anisakis simplex and 26 patients diagnosed with visceral larva migrans (VLM) caused by Toxocara canis were studied employing commercial diagnostic kits and "in house" assay kits. Cross-reactivity observed was greater when using "in house" assay kits, suggesting that T. canis excretory-secretory antigens were not only recognized by antibodies from patients with RAU but with greater intensity compared to the A. simplex excretory-secretory antigens.
منابع مشابه
ELISA antibody determination in patients with anisakiosis or toxocariosis using affinity chromatography purified antigen.
One of the fundamental aspects of a parasitic infection diagnosis is the use of adequate antigens to develop specific and sensitive immunoassays. This fact is especially complicated in nematode infection cases because of the high cross-reactivity among different parasites in this group. We performed an evaluation of Anisakis simplex antigens purified by affinity chromatography. We used sera fro...
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ورودعنوان ژورنال:
- Acta tropica
دوره 89 1 شماره
صفحات -
تاریخ انتشار 2003